Devyser UPD-15, 8-A016

Devyser UPD-15, 8-A016-25tests

The Devyser UPD-15 diagnostic kit
Devyser UPD-15 relies on amplification of tetra nucleotide STRmarkers in order to minimize formation of stutter bands and thereby
simplifying results interpretation. Reducing stutter is especially important when two alleles from the
individuals investigated are close in size. Devyser UPD-15 also includes STR-markers on chromosomes
13 and 18 to facilitate the exclusion of maternal contamination by absence of non-inherited maternal
alleles in the proband sample. Moreover, detection of maternally and paternally inherited fetal alleles
from chromosomes 13 and 18 allows built-in sample identification of the proband, maternal and paternal samples. Four out of nine STR-markers that are specific for chromosome 15 are located within the
15q11-13 deletion region.